Cushing ta ciwo a cikin kare.

A cikin yanayi mai wahala, glandan adrenal na dabbobi da mutane suna samar da hormone cortisol. Yana motsa jiki don yaƙar matsaloli. Lokacin da maida hankali na cortisol ya kai wani matakin, ƙarin samar da shi yana tsayawa. Idan ka'idar ta karye, jiki yana ci gaba da kasancewa a shirye don damuwa, wanda ba a can ba. Rashin lafiyar hormonal yana faruwa - hyperadrenocorticism (GAC), ko Cushing's syndrome. A cikin karnuka, wannan Pathology yana rushe metabolism, yana haifar da hauhawar hauhawar jini da sauran sakamako mara kyau.

Siffofin cutar

Haɗin kai da samar da cortisol yana faruwa a cikin glandar adrenal na dabba. Sigina don samar da hormones na damuwa shine sakin hormone adrenocorticotropic (ACTH) ta hanyar glandan pituitary, wanda shine sakamakon abubuwan da ba su da kyau. Lokacin da matakin cortisol ya kai matsakaicin ƙima, glandan pituitary ya daina samar da ACTH, sakamakon haka, abun ciki na cortisol shima yana raguwa.

Wani lokaci hormone damuwa yana fara ɓoye ko da a cikin yanayin al'ada, in babu wani abu a rayuwar dabbar. A lokaci guda kuma, jikin kare yana cikin tsammanin damuwa na dogon lokaci (watanni ko shekaru) har sai an gano cutar. Wannan yana haifar da gajiya ta jiki da ta hankali, raguwa mai yawa a cikin rigakafi, haɓaka cututtuka na tsarin gabobin da yawa, da kuma tsufa.

Af, yana da mahimmanci a lura da wannan batu: a cikin maganin ɗan adam, ra'ayoyin "Cushing's Cushing" da "Cushing's Syndrome" sun bambanta da juna. A cikin akwati na farko, shi ne ilimin cututtuka na yanayin neuroendocrine, a cikin akwati na biyu, cuta ce da ke hade da ciwace-ciwacen ƙwayoyi na adrenal gland. A cikin magungunan dabbobi, ana shafe irin waɗannan bambance-bambance, kuma ta hanyar "Cushing's syndrome" masana suna nufin rashin lafiya da ke haifar da wani abu na kowane asali.

Dalilan Cushing's Syndrome a cikin karnuka (classification pathogen)

Akwai dalilai guda uku na haɓakar cutar Cushing a cikin karnuka.

1. Ciwon daji na Pituitary. Suna haifar da wuce haddi na hormone adrenocorticotropic a cikin jini, wanda, bi da bi, yana haifar da haɓakar hyperplasia na biyu na glandan adrenal da kuma samar da adadi mai yawa na cortisol.
2. Ciwon daji na adrenal gland. Neoplasms suna da ikon fitar da hormone mai damuwa mai zaman kansa.
3. Iatrogenic dalilai. Cin abinci mara kyau na glucocorticoids ko ACTH (mafi yawa).

Ciwon Cushing mai dogaro da Pituitary a cikin karnuka yana faruwa a cikin 80-85% na lokuta. Kusan 10-15% sune neoplasms na glandar adrenal. A lokaci guda kuma, likitocin dabbobi sun lura cewa karuwa a matakin cortisol wanda ciwace-ciwacen glandon adrenal ya haifar ba koyaushe yana faruwa ba, amma wani lokacin (rashin lafiya).

Wanene ke cikin haɗari?

Karnukan manya sun fi kamuwa da cutar GAC (Cushing's syndrome). Bugu da kari, a cikin tsufa, nau'in cutar adrenal yana mamaye dabbobi, ba wanda ya dogara da pituitary ba. Babu bayyanannen jinsi da dogaron jinsi. Likitoci kawai sun lura cewa ciwon Cushing galibi masu shi ne ke magance su dachshund, poodles, pinscher.

Ta yaya cutar Cushing ke bayyana?

A cikin karnuka, hyperadrenocorticism yana rinjayar duk tsarin gabobin, don haka alamun cutar sun bambanta.

• Daga tsarin urinary: babban adadin fitsari na yau da kullun da aka fitar (a lokaci guda, ƙãra ƙishirwa), yawan buƙatun yin fitsari.
• Daga gefen fata: ɓacin rai na fata, asarar elasticity, toshe ɓawon burodi, bushewa, flaking.
• Daga gefen gashi: asarar gashi mai mahimmanci, gashin gashi (na farko a kan gangar jikin, kuma a ƙarshe a kan gabobin, kai, wutsiya).
• Daga tsarin haihuwa: atrophy testicular, ƙarewa estrus.

Daga cikin sauran alamun cutar Cushing: atrophy tsoka, gazawar numfashi, sagging ciki, yawan ci wanda baya haifar da gamsuwa, slurred magana.

Alamun suna tasowa a hankali, suna bayyana watanni da yawa bayan bayyanar cutar. A tsawon lokaci, dabba yana tasowa wasu cututtuka, misali, ciwon sukari, osteoporosis, arrhythmia, cututtuka na gastrointestinal. Hali da bayyanar dabba suna canzawa - kare ya juya ya zama halitta mai rauni, tare da ƙananan gaɓoɓin da suka yi hasarar nauyi, ciki mai raguwa da sternum mai nutsewa.

Ganewar cutar Cushing a cikin kare

Hyperadrenocorticism a cikin karnuka ana gano su ta hanyoyi daban-daban. Da farko, a liyafar, likitan dabbobi zai bincika dabbar, yin hira da mai shi game da gunaguni, yanayin rayuwa, shekaru da halaye na alamun bayyanar cututtuka, ɗaukar jini don bincike na asibiti da biochemical. A cikin gwaje-gwajen jini na dabbobi masu fama da cutar Cushing, ana lura da karuwa a matakin leukocytes, neutrophils, cholesterol da triglycerides, raguwar abun ciki na eosinophils, da urea sau da yawa.

Hakanan ana iya sanya ɗalibin:

• bincike ta amfani da gwaje-gwaje (ACTH-stimulating, gwajin cortisol / creatinine, gwajin dexamethasone);
• radiyo (gano osteoporosis, mineralization na adrenal gland shine yake);
• Duban dan tayi na adrenal gland (don bambance tushen pathology);
• CT scan ko MRI na adrenal gland, pituitary gland shine yake (gano neoplasms).

Maganin ƙwayoyi na GAC ​​/ Cushing's syndrome a cikin karnuka

Jiyya na Cushing ta ciwo a cikin karnuka tare da kwayoyi ana gudanar da shi a cikin rashin ciwace-ciwacen ƙwayoyi a cikin glandan adrenal da glandan pituitary ko ƙananan girman su. Manufar ita ce rage matakan hormone damuwa zuwa al'ada. Tsarin magani ya haɗa da takamaiman magunguna da magunguna. Na farko yana hana samar da hormones ta glandon adrenal ko haifar da atrophy na cortex ("Vetoril" da "Mitotan", bi da bi).

Magungunan alamomi sun haɗa da:

• antitumor (yana hana ci gaban neoplasms);
• anti-mai kumburi, antifungal na waje (ga fata);
• masu goyon bayan zuciya;
• hypotensive (daidaita hawan jini) da sauransu.

Idan an gano ciwace-ciwacen yanayi a cikin kare, ana nuna chemotherapy da radiation far. Game da asalin cutar iatrogenic, magungunan da suka haifar da cutar Cushing ana soke su a hankali kuma a ƙarƙashin ikon gwaje-gwajen dakin gwaje-gwaje.

Magani mai aiki

Idan zai yiwu a cire ciwace-ciwacen ƙwayoyi na glandan adrenal ta hanyar tiyata, yana da kyau a zabi wannan hanya, tun lokacin da aikin ya ba da kyakkyawan hangen nesa. Idan akwai bambance-bambancen da ke dogara da pituitary na pathology, aikin tiyata shima ya fi kyau. Duk da haka, gudanar da aikin yana buƙatar kwarewa mai yawa, kuma a cikin na biyu - kasancewar kayan aiki na musamman. Bugu da ƙari, tiyata a kan glandon pituitary zai iya haifar da ci gaba da rikitarwa da mutuwa. Daga cikin mummunan sakamakon, ya kamata a lura: cire wani yanki mafi girma fiye da yadda ake bukata na gland shine zubar jini.

Tiyata kau da adrenal gland yana haifar da rashi na hormones da ake bukata don rayuwa, don haka bayan jiyya, kare za a wajabta a rayuwa na hormone far.

Tare da ciwo na Cushing, ba a yi aikin ba idan an gano metastases a cikin dabba, akwai cututtuka masu tsanani na yanayi na yau da kullum, babu yiwuwar yin amfani da maganin sa barci da sauran lokuta.

Yadda za a kula da kare a lokacin jiyya da kuma lokacin gyarawa?

Kula da kare da cutar Cushing kawai kamar yadda likita ya umarta. Ba a yarda da amfani da hanyoyin jama'a ba. Ana buƙatar mai mallakar dabba don bin shawarwarin - makirci, lokacin magani, tsawon lokaci, da dai sauransu.

Ya kamata a ba da kulawa sosai ga abincin dabba. Abincin ya kamata ya ƙunshi duk abubuwan gina jiki da bitamin. Abincin ya kamata ya zama mai narkewa cikin sauƙi, yana motsa samar da enzymes na pancreas da sauran gabobin gastrointestinal tract, da tallafawa aikin hanji. Idan mai shi ba shi da damar yin menu don dabbar da kansa, za ku iya neman taimakon ƙwararru ko saya abinci na masana'antu na musamman. Abincin kare ya kamata ya zama abincin abinci, bisa ka'idar "sau da yawa, amma kadan kadan."

Mai shi yana buƙatar shirya cewa magani zai iya ɗaukar watanni da yawa, kuma a cikin yanayin tiyata - don sauran rayuwar kare. Bugu da ƙari, kare zai iya haifar da irin wannan sakamako na Cushing's syndrome kamar cututtuka na tsarin zuciya da jijiyoyin jini, glandar thyroid, gabobin haihuwa, hanta da kodan. Wajibi ne a kula da yanayin fata, don hana fungal da sauran cututtuka.

Har yaushe karnuka masu ciwon Cushing ke rayuwa?

Bisa kididdigar da aka yi, tsawon rayuwar dabbobin da ke fama da ciwon GAC / Cushing shine, a matsakaita, shekaru uku. Wannan mai nuna alama ya dogara da dalilai masu yawa: shekarun dabba, nau'in cutar, farkon ko farkon farkon jiyya, kasancewar cututtuka na yau da kullum. A matsayinka na mai mulki, ana lura da cikakkiyar farfadowa tare da bambance-bambancen iatrogenic na ciwo kuma a cikin yanayin da aka fara tuntuɓar asibitin, kafin mummunan lalacewa ga gabobin ciki ya faru. Yanayin rayuwa da magani (gyara) na dabba, da kuma halin masu shi game da shi, suna da mahimmanci.

Shin zai yiwu a guje wa cutar?

Babu takamaiman matakan kariya don cutar Cushing. Amma ana iya rage haɗarin kamuwa da cutar. Don wannan, masana sun ba da shawarar:

• a kai a kai ziyarci asibitin don gwajin rigakafi da gwaje-gwaje, musamman idan kare yana cikin ƙungiyar haɗari;
• lokacin da ake ba da magungunan hormonal, bin shawarwarin likita sosai, kada ku shiga cikin maganin kai, kada ku yi amfani da hanyoyin jama'a (ba tare da izinin likitan dabbobi ba);
• kula da abincin dabba;
• kar a yi watsi da ko da qananan canje-canje a cikin halin dabba da salon rayuwa.

Lokacin da aka gano kare yana da ciwon Cushing, kulawa da kulawa da kyau zai inganta yanayin rayuwa kuma ya kara tsawonsa. Kula da dabbar ku da ƙauna kuma zai rama. Kula da kanku, ƙaunatattunku da abokai ƙafa huɗu.